We strongly suggest that you keep a spare cartridge available to place on the printer while you refill this cartridge to prevent the ink from drying out.
Step 1) Locate the bottom of the cartridge. This is where the screen filter is located and the large exit hole. Tape over the exit hole. This is important!
Step 2) Put the cartridge on some paper towels in an area where you can tolerate a spill.
Step 3) Drill a #55 or 1/16 inch hole into the top of the cartridge. You may use the small hole on the top back side as a starter hole. (Don't worry about shavings -- the internal foam will filter them out.) Drill the hole as close to directly above the exit hole as possible for best results.
You may also decide to heat a large paper clip in a flame and melt your way into the cartridge instead of drill. Be careful not to burn your fingers!
Be sure to drill through the plastic baffle into the foam sponge.
Step 4) Fill the syringe bottle with ink and insert fully vertically through the hole on top. (If you have placed the cartridge on the surface in front of you, the needle should be vertical.) You will feel the resistance of the foam. Continue until you are almost at the bottom of the foam chamber, but do not push all the way through.
Step 5) Inject the ink very S-L-O-W-L-Y. Too fast and you will "vapor lock" the foam because air bubbles will form.
Step 6) When ink comes out the top -- the cartridge is full. Expect some bubbles to come out first.
Step 7) Remove the tape covering the bottom exit hole.
Step 8) Set up above (over) a paper towel for 5 minutes and let the cartridge drip. Be sure that the cartridge does not touch the paper towel, or the ink will be pulled out of the cartridge.
Step 9) For best results, wait until the 'last' drip is hanging at the exit hole. Wipe this drip off and immediately insert into your printer. Be sure to follow the insertion instructions.
The most important issue is to make sure that there is a continous flow of ink from the sponge to the printhead. If not, you have air in the line (an air bubble), which will stop the flow of ink.
Clean the printhead only if the cartridge doesn't print or prints in streaks.
Follow the directions in the printer manual.